摘要
本文介绍一种新型的头部含抗菌素的硅橡胶导尿管。该管药头部应用单组份硫化硅橡胶和硫酸卡那霉素,按1:1混合在室温下固化制成。每个药头含硫酸卡那霉素20~30万单位。体外测试证实能释放有效抑菌浓度(>20单位/毫升),持续20天左右。临床试用28例的资料表明应用该管后尿内白细胞明显减少。17例测定尿内卡那霉素,有15例大于20单位/毫升,12例使用该管前尿培养阳性者中有10例复查尿培养,结果有8例转为阴性。
A new type silicone rubber catheter with a kanamycin containing tip is introduced:The tip is made up of 1:1(W/W)kanamycin sulfate(200-300 thousand units)andvulcanized silicone rubber.On contact with urine it releases continuously over 20 u/mlof kanamycin for 20 days.This catheter had been used clinically in 28 patients.Theurine WBC counts decreased in all cases and bacteria culture of urine became negativein 80%.
出处
《上海医学》
CAS
1982年第1期11-13,60,共4页
Shanghai Medical Journal
