睾丸肿瘤——上海市23所医院586例临床分析

TESTICULAR TUMORS A REPORT OF 586 CASES FROM 23 HOSPITALS OF SHANGHAI

本文报道上海市23所医院30年来收治的睾丸肿瘤586例。年龄为8个月至83岁,其中347例(59.2%)在20~40岁。本组生殖细胞瘤占84.8%,非生殖细胞瘤占7.9%,继发性肿瘤4.2%。精原细胞瘤的5年及10年生存率分别为45%及18.6%。非精原细胞生殖细胞瘤的5年及10年生存率分别为26.4%及16%。术后放射治疗对精原细胞瘤患者有效,最长的已生存21年:非精原生殖细胞瘤宜采用睾丸切除和后腹膜淋巴结清除术。

586 cases of testicular tumors admitted to 23 hospitals of Shanghai in the past 30years were analysed.The ages ranged from 8 months to 83 years old and 347 cases(59.2%)were between 20—40 years of age.Embryonal carcinoma and malignant tera-toma were more frequently seen in early childhood.There were 502 cases(84.8%)ofgerm cell tumors,47(7.9%)non-germ cell tumors and 25(4.2%)metastatic tumors,mostly lymphosarcoma.The S-year and 10-year survival rates of seminoma were 45.6%and 18.6%,that of non-seminomatous germ cell tumors were 26.4%and 16%respec-tively.The better prognosis in the former was due to the effectiveness of radiationtherapy for seminoma.68 cases of non-seminomatous germ cell tumor were treated byorchioectomy and radical resection of retroperitoneal lymph nodes,giving a 5-yearsurvival rate of 45%;while in cases without radical resection of retroperitoneal lymphnodes all died within 2 years.If combined chemotherapy were used the therapeuticeffect would be further enhanced.