儿童、青少年鼻咽恶性肿瘤91例的临床和病理分析

A CLINICO-PATHOLOGICAL STUDY OF NINETY ONE CASES OF MALIGNANT NASOPHARYNGEAL TUMOURS IN CHILDREN AND ADOLESCENTS

鼻咽恶性肿瘤不仅为成人上呼吸道最常见的恶性肿瘤之一,在儿童、青少年组也并不少见。儿童鼻咽恶性肿瘤占儿童所有恶性肿瘤的1%左右,占所有鼻咽恶性肿瘤的2~18%。

A total of 91 cases of malignant nasopharyngeal tumours in children and adolescents were reported.The distribution of age and sex,main symptoms,clinical staging,relation between histological type and clinical behavior,treatment,prognosis and cause of death were discussed.81 cases(89%of total)were of stageⅢandⅣwhile only 10 cases(11%)of stageⅠandⅡ.73 cases were poorly differentiated carcinomas and 15 cases malignant lymphomas.The carcinoma/sarcoma ratio was 5.1:1.All patients were treated with irradiation.The average 5-year survival rate was 67.4%,while in stageⅠandⅡ100%.This analysis revealed that,in comparison with adults,children and adolescents had a higher incidence of sarcoma,a higher 5-year survival rate and a higher proportion of advanced oases.