摘要
子宫腺肌病可导致不孕和流产,可增加体外受精-胚胎移植(IVF-ET)的流产率、降低活产率和临床妊娠率,也增加产科和新生儿相关并发症。经阴道超声已成为子宫腺肌病的一线诊断方法,但需提高诊断率。子宫腺肌病合并不孕症的治疗方法包括药物、手术、介入治疗和辅助生殖助孕治疗等。一般情况下可推荐首选IVF,一般推荐GnRH-a的应用和全胚冷冻策略。针对子宫腺肌病的诊断、非IVF治疗方法的效果、GnRH-a预处理以及鲜胚、冻胚移植比较等问题仍需进行更多研究。
Adenomyosis can cause infertility and miscarriage,increase the miscarriage rate of in vitro fertilization intracytoplasmic sperm injection and embryo transfer(IVF-ET),reduce the live birth rate and clinical pregnancy rate,and increase obstetric and neonatal complications.Transvaginal ultrasound has become the first-line diagnostic method of adenomyosis,but the accuracy needs to be improved.The treatment of adenomyosis complicated with infertility includes drug,surgical,interventional therapy and assisted reproduction therapy,et al.IVF is generally recommended as the first choice,and GnRH-a and freeze-all strategy are also recommended.More research is needed to explore the diagnosis of adenomyosis,efficacy of non-IVF treatment,pretreatment of GnRH-a,and comparison of fresh versus frozen embryo transplantation.
作者
颜磊
陈子江
YAN Lei;CHEN Zijiang(Department of Gynecology,Center for Reproductive Medicine,Shandong University,Jinan 250021,Shandong,China)
出处
《山东大学学报（医学版）》
CAS
北大核心
2022年第7期43-47,共5页
Journal of Shandong University:Health Sciences
基金
国家自然科学基金(82072627)
关键词
子宫腺肌病
不孕症
体外受精
胚胎移植
Adenomyosis
Infertility
In vitro fertilization intracytoplasmic sperm injection
Embryo transfer
