二丹红藤败酱汤结合艾灸治疗慢性盆腔炎临床疗效观察

Clinical Effective Observation of Using Erdan Hongteng Baijiang Decoction Combined with Mmoxibustion in the Treatment of Chronic Pelvic Inflammatory Disease

目的:探究二丹红藤败酱汤结合艾灸治疗慢性盆腔炎临床效果。方法:研究纳入慢性盆腔炎患者105例(2020年3月~2021年6月收治),并以随机数字表法将105例患者随机分为两组,对照组和观察组,分别52例、53例,对照组予头孢曲松钠与甲硝唑结合治疗,观察组予头孢曲松钠与甲硝唑结合治疗+二丹红藤败酱汤结合艾灸治疗,比较各组患者治疗效果、治疗前后局部体征(子宫、附件、宫骶韧带)评分变化、中医症状积分(下腹刺痛或胀痛、带下量多、脘腹胀满、经前乳房胀痛、情志抑郁、烦躁等)变化、血清白介素-2(IL-2)、白介素-8(IL-8)及肿瘤坏死因子α(TNB-α)水平变化、不良反应。结果:与对照组(82.69%)比较,观察组(96.23%)有效率更高(P<0.05);治疗前,两组患者局部体征(子宫、附件、宫骶韧带)评分、中医症状积分(下腹刺痛或胀痛、带下量多、脘腹胀满、经前乳房胀痛、情志抑郁、烦躁等)及IL-2、IL-8、TNB-α等指标比较无显著性差异(P>0.05),治疗后两组患者局部体征(子宫、附件、宫骶韧带)评分、中医证候积分(下腹刺痛或胀痛、带下量多、脘腹胀满、经前乳房胀痛、情志抑郁、烦躁等)及IL-2、IL-8、TNB-α等指标均改善,且观察组优于对照组(P<0.05);对照组1例恶心,观察组1例头晕,不良反应发生例数均较少。结论:慢性盆腔炎患者采取二丹红藤败酱汤与艾灸治疗结合临床效果良好,安全可行,值得应用。

Objective:To explore the clinical effect of using Erdan Hongteng Baijiang Decoction combined with moxibustion in treating chronic pelvic inflammatory disease.Methods:This study included 105 patients with chronic pelvic inflammatory disease(admitted from March 2020 to June 2021),and reduced 105 patients by the random number table method and randomly divided into two groups,a controlled group and an observation group,52 cases and 53 cases,respectively,were given Ceftriaxone Sodium and Mmetronidazole combined treatment of the controlled group.The observation group was treated with Ceftriaxone Sodium combined with Metronidazole and Erdan Hongteng Baijiang Decoction combined with moxibustion.Groups were compared before and after the treatment effect,local signs(uterus,attachment,palace sacral ligaments)score changes,TCM syndrome integral(ventral stabbing pain or tenderness,aginal discharge capacity was much,often abdominal distension full,premenstrual breast tenderness,modern depression,irritability,etc.)change,serum interleukin-2(IL-2)and interleukin-8(IL-8)and tumor necrosis factor alpha(TNB-alpha)level changes,adverse reactions.Results:Compared with the controlled group(82.69%),the observation group(96.23%)had higher effective rate,P<0.05.Before treatment,the scores of local signs(uterus,adnexa,miacral ligament),TCM syndrome scores(lower abdomen tingling or distention pain,lower band amount,abdominal distention,premenstrual breast distention pain,depression,irritability,etc.),IL-2,IL-8,TNB-αand other indicators in the 2 groups were compared,P>0.05.After treatment,the scores of local signs(uterus,adnexa,and uterosacral ligament),TCM syndrome scores(lower abdomen tingling or distention pain,lower band quantity,abdominal distention,premenstrual breast distention pain,depression,irritability,etc.),IL-2,IL-8,TNB-αand other indicators were improved in each group.After treatment,the scores of local physical signs(uterus,adnexa,uterosacral ligament),TCM syndrome scores(lower abdomen tingling or distention pain,more bands,depression or irritability,premenstrual breast distention,abdominal distention,etc.),IL-2,IL-8,TNB-αand other indexes in the observation group were better than those in the controlled group,P<0.05.There was 1 case of nausea in the controlled group and 1 case of dizziness in the observation group.Conclusion:The combination of Erdan Hongteng Baijiang Decoction and moxibustion therapy for chronic pelvic inflammatory disease patients has good clinical effect,safe and feasible,and is worthy of application.