脑卒中后认知功能障碍研究进展

Progress in post-stroke cognitive impairment

脑卒中后认知功能障碍(post-stroke cognitive impairment,PSCI)是急性脑血管病事件发生后出现的认知功能障碍或是原有认知功能障碍的加重。PSCI不仅影响脑卒中后患者的生活质量,也影响患者对规范治疗的判断力和依从性,是影响患者生存时间的重要因素。本文旨在对PSCI的临床表现、流行病学、发病机制、影响因素、诊断步骤、神经心理学评估、影像学表现以及干预和治疗的最新进展进行综述,重点聚焦于PSCI发病机制和影像学表现的最新进展,以期为PSCI的早期诊断和防治策略提供参考依据。

Post-stroke cognitive impairment(PSCI)is the cognitive impairment or the aggravation of the original cognitive impairment after the occurrence of acute cerebrovascular disease.PSCI not only affects the quality of life of the patients after stroke,but also affects the patients’judgment and compliance with the standard treatment,so it is an important factor affecting the survival time of the patients.The purpose of this paper is to review the latest progress in clinical manifestations,epidemiology,pathogenesis,influencing factors,diagnostic procedures,neuropsychological evaluation,imaging performance,and intervention and treatment of PSCI,focusing on the latest progress in the pathogenesis and imaging performance of PSCI,in order to provide references for the early diagnosis and prevention strategies of PSCI.