经颅磁刺激治疗对抑郁症疗效与社会功能的影响

Effect of transcranial magnetic stimulation on depression and social function

目的:观察经颅磁刺激治疗对抑郁症疗效与社会功能的影响。方法:选取我院抑郁症患者68例(2018年2月至2019年3月),随机分为常规治疗的对照组(34例)与经颅磁刺激治疗的观察组(34例),观察患者社会功能、神经递质指标、抑郁症状、认知功能、不良反应发生率。结果:治疗后,观察组PSP评分(63.21±8.62)分,均高于对照组,P<0.05;治疗后,观察组5-HT(352.18±5.11)ng/mL,NE(11.74±2.38)ug/mL,均高于对照组,P<0.05;观察组治疗后4周、8周抑郁症状、认知功能评分低,P<0.05;观察组(5.88%)低于对照组(23.53%),P<0.05。结论:给予抑郁症患者经颅磁刺激治疗,能提高患者社会功能,促进神经递质指标系统恢复,减轻患者抑郁症状,提高认知功能,且不良反应少,值得借鉴。

Objective:To observe the effect of transcranial magnetic stimulation on depression and social function.Methods:68 patients with depression in our hospital(February 2018 to March 2019)were randomly divided into conventional treatment control group(34 cases)and transcranial magnetic stimulation treatment observation group(34 cases).The patients’social function,neurotransmitter indexes,depressive symptoms,cognitive function and the incidence of adverse reactions were observed.Results:After treatment,the PSP score(63.21±8.62)in the observation group was higher than that in the control group(P<0.05);after treatment,the 5-HT(352.18±5.11)ng/ml and ne(11.74±2.38)UG/ml in the observation group were higher than those in the control group(P<0.05);the scores of depressive symptoms and cognitive function in the observation group were lower at 4 and 8 weeks after treatment(P<0.05);(5.88%)in the observation group was lower than that in the control group(23.53%),P<0.05.Conclusion:Transcranial magnetic stimulation can improve patients’social function,promote the recovery of neurotransmitter index system,reduce patients’depressive symptoms,improve cognitive function,and have less adverse reactions,which is worthy of reference.