拉贝洛尔配合硝苯地平治疗妊娠期高血压的效果及对患者血液流变学指标的影响

The Effect of Labetalol Combined with Nifedipine in the Treatment of Hypertension during Pregnancy and its Influence on the Hemorheological Indexes of Patients

目的分析拉贝洛尔配合硝苯地平治疗妊娠期高血压的效果。方法选择2019年1月—2020年8月到本院就诊的80例妊娠期高血压患者为研究对象,采用抛硬币法分为对照组(n=40),观察组(n=40),对照组采用硝苯地平治疗,观察组在对照组的基础上配合拉贝洛尔治疗,评估两组患者的治疗效果。结果观察组总有效高于对照组(95.0%vs 77.50%),治疗后血液流变学及动力学改善幅度高于对照组,不良结局低于对照组(20.0%vs 42.50%)(P<0.05)。结论拉贝洛尔配合硝苯地平治疗妊娠期高血压,效果理想。

Objective To analyze the effect of labetalol combined with nifedipine in the treatment of hypertension during pregnancy.Methods A total of 80 patients with gestational hypertension who visited our hospital from January 2019 to August 2020 were selected as the research objects,and were divided into control group(n=40),observation group(n=40),control group by coin toss method Nifedipine was used for treatment,and the observation group was treated with labetalol on the basis of the control group,and the therapeutic effect of the two groups was evaluated.Results The observation group’s total effectiveness was higher than that of the control group(95.0%vs 77.50%),the improvement of hemorheology and kinetics after treatment was higher than that of the control group,and the adverse outcome was lower than that of the control group(20.0%vs 42.50%)(P<0.05).Conclusion Labetalol combined with nifedipine in the treatment of hypertension during pregnancy,the effect is ideal.