妇科肿瘤治疗中铂类抗癌药物的应用研究

Application of Platinum Anticancer Drugs in the Treatment of Gynecological Tumors

目的研究铂类抗癌药物应用至妇科肿瘤治疗当中的效果。方法选取时间为2018年1月—2019年1月期间本院收诊的100例妇科肿瘤患者,按照收诊的先后次序分组,其中50例妇科肿瘤患者给予紫杉醇+卡铂化疗方式治疗,将其划分至对比组,剩余50妇科肿瘤患者给予紫杉醇+顺铂化疗方式治疗,将其划入观察组,比较两组妇科肿瘤患者采用不同铂类抗癌药物化疗方治疗6个月后的疗效,同时详细阐述应用期间发生的不良反应。结果观察组治疗总效率为92.0%略高于对比组90.0%,两组治疗总效率比较差异无统计学意义(P>0.05);观察组总不良反应发生率18.0%略低于对比组20.0%,比较差异无统计学意义(P>0.05)。结论铂类抗癌药物应用至妇科肿瘤当中效果显著,临床应用前景广泛,对改善患者的病情,提升生活质量,改善其预后的意义重大,故值得临床借鉴和推广。

Objective To study the effect of platinum anticancer drugs in the treatment of gynecological tumors.Methods From January 2018 to January 2019,100 cases of gynecological tumors were selected,Grouped according to the order of visits,Among them,50 patients with gynecological tumors were treated with paclitaxel carboplatin chemotherapy,Divide it into contrast groups,The remaining 50 patients with gynecologic tumors were treated with paclitaxel,cisplatin,To the observation group,Compared with the two groups of gynecological tumor patients with different platinum anticancer drugs chemotherapy after 6 months of treatment,At the same time,the adverse reactions occurred during the application were described in detail.Results The total therapeutic efficiency of observation group was 92.0%,Compared with each other P>0.05;The incidence of total adverse reactions in the observation group was 18.0%slightly lower than that in the contrast group 20.0%,Each other P>0.05.Conclusion The application of platinum anticancer drugs to gynecologic tumors has remarkable effect,The clinical application prospect is wide,To improve the patient’s condition,Improving the quality of life,To improve their prognosis,Therefore,it is worth clinical reference and promotion.