MRI在结直肠癌患者恶性程度分级中的诊断价值

Diagnostic Value of MRI in Malignant Grade of Colorectal Cancer Patients

目的探讨在结直肠癌恶性程度分级中,核磁共振成像(MRI)的技术的临床应用价值。方法选取浙江省义乌市中心医院接诊的结直肠癌患者53例,对其实施MRI诊断,并以病理诊断结果为标准,对MRI的ADC值的变化进行分析。结果病例结果:低分化腺癌4例,中分化腺癌42例,高分化腺癌7例;平扫T1WI为等信号,T2WI为稍高信号,DWI为高信号或者混杂高信号,ADC为明显的低信号变化;高分化结直肠癌ADC值高于中分化、低分化,中分化结直肠癌ADC值高于低分化,差异有统计学意义(P<0.01);针对中分化与低分化的诊断中,ADC值的应用敏感度、特异度为88.68%、79.25%;针对高分化与中分化的诊断中,ADC值的应用敏感度、特异度分别为77.36%、79.25%;针对高分化与低分化的诊断中,ADC值的应用敏感度、特异度分别为77.36%、100.00%。结论在结直肠癌诊断中,MRI可有效实现对其恶性程度的分级鉴别,具有较高的灵敏度和特异度,值得推广。

Objective To explore the clinical application value of magnetic resonance imaging(MRI)in grading the malignant degree of colorectal cancer.Methods 53 patients with colorectal cancer in Yiwu Central Hospital were selected and diagnosed by MRI.The ADC value of MRI was analyzed according to the pathological diagnosis results.Results There were 4 poorly differentiated adenocarcinomas,42 moderately differentiated adenocarcinomas and 7 highly differentiated adenocarcinomas.On plain scan,T1WI was iso-signal,T2WI was slightly hyper-signal,DWI was hyper-signal or mixed hyper-signal,and ADC was markedly low-signal.The ADC value of highly differentiated colorectal cancer was higher than that of moderately differentiated and poorly differentiated colorectal cancer,with a significant difference(P<0.01).The sensitivity and specificity of ADC were 88.68%and 79.25%in the diagnosis of moderately differentiated and poorly differentiated,77.36%and 79.25%in the diagnosis of highly differentiated and poorly differentiated,and 77.36%and 100.00%in the diagnosis of highly differentiated and poorly differentiated.Conclusion In the diagnosis of colorectal cancer,MRI can effectively differentiate the malignant degree of colorectal cancer.It has high sensitivity and specificity,and is worth popularizing.