神经内镜下与显微镜下经鼻蝶入路手术切除垂体腺瘤的效果研究

Study on the Effect of Transsphenoidal Surgery for Pituitary Adenoma under Neuroendoscope and Microscope

目的探讨神经内镜下与显微镜下经鼻蝶入路手术切除垂体腺瘤的效果研究。方法现选取2017年4月—2018年3月入住广西钦州市第一人民医院需接受经鼻蝶入路手术治疗的垂体腺瘤患者88例,按切除方式分为两组,各44例,对照组予以显微镜下经鼻蝶入路手术切除,研究组予以神经内镜下经鼻蝶入路手术切除,比较两组各项手术指标、住院时长、术中出现脑脊液漏的概率、术后出现并发症的概率以及心理状态变化情况。结果对照组手术用时、手术出血量、住院时长都高于研究组(P<0.05);对照组术中出现脑脊液漏的概率高于研究组(P<0.05),两组术后出现并发症的概率差异无统计学意义(P>0.05);治疗后对照组心理状态差于研究组(P<0.05)。结论在手术治疗垂体腺瘤患者的过程中,神经内镜下与显微镜下经鼻蝶入路手术切除都获得了明显实效,但神经内镜下经鼻蝶入路手术切除用时较短、术中出现脑脊液漏的概率较低、缩短住院时长,可在临床上进一步广泛推广与应用。

Objective To study the effect of transsphenoidal surgery for pituitary adenoma under neuroendoscope and microscope.Methods 88 patients with pituitary adenoma who were admitted to the First People’s Hospital of Qinzhou City from April 2017 to March 2018 and required transnasal sphenoid approach surgery were selected and divided into two groups according to the method of resection,44 cases in each group.The control group shall be under the microscope nasal surgical removal of the butterfly into the road,the team shall be neural endoscopic nasal surgical removal of the butterfly into the road,two groups of operation indicators,hospitalization duration,intraoperative cerebrospinal fluid leakage probability,the probability of the postoperative complications,and mental state changes were compared.Results The duration of operation,blood loss and length of hospital stay in the control group were all higher than that in the study group(P<0.05).The probability of intraoperative CSF leakage in the control group was higher than that in the study group(P<0.05),and there was no difference in the probability of postoperative complications between the two groups(P>0.05).After treatment,the psychological status of the control group was worse than that of the study group(P<0.05).Conclusion In the process of surgical treatment of patients with pituitary adenoma,nerve under endoscope and microscope nasal adjustment approach surgical removal of all obtained the obvious actual effect,but the neural endoscopic nasal adjustment approach surgery time is shorter,intraoperatie cerebrospinal fluid leakage probability is low,shorten hospitalization time,can be further popularized and applied widely in clinic.