中药结合高压氧治疗血管源性头痛的疗效分析

Curative Effect of Traditional Chinese Medicine Combined with Hyperbaric Oxygen in the Treatment of Vascular Headache

目的探讨中药结合高压氧治疗对血管源性头痛患者的疗效。方法选取2016年3—9月包头市第四医院神经内科门诊和住院收治的中度以上血管源性头痛患者92例,按照随机数字表法分为高压氧组46例和药物组46例,药物组患者给予丹珍头痛胶囊3粒/次,3次/d口服,高压氧组患者给予丹珍头痛胶囊结合高压氧治疗,治疗过程中高压氧组删失4例,药物组删失2例。治疗18 d后评价临床疗效,发病24 h内、治疗第9、18天时视觉模拟评分法(VAS)、头痛量表(HIT-6)评分法评定头痛程度。结果治疗18 d后,高压氧组总有效率高于药物组〔100.0%(44/44)与76.2%(32/42)〕(χ~2=11.855,P=0.001)。高压氧组和药物组患者发病24 h内、治疗第9、18天时VAS、HIT-6评分比较,差异有统计学意义(P<0.05);其中治疗第9、18天时VAS、HIT-6评分低于发病24 h内,治疗第18天时VAS、HIT-6评分低于治疗第9天(P<0.05)。发病24 h内、治疗第18天时高压氧组与药物组患者VAS、HIT-6评分比较,差异无统计学意义(P>0.05);治疗第9天时高压氧组患者VAS、HIT-6评分低于药物组(P<0.05)。结论中药结合高压氧治疗血管源性头痛急性期患者疗效显著,可明显改善VAS、HIT-6评分,值得临床推广应用。

Objective To investigate the combination of Chinese medicine combined with hyperbaric oxygen therapy on patients with vascular headache.Methods 92 patients with moderate or above vascular headache were selected from the outpatients and inpatients of Neurology Department of Baotou fourth hospital from March to September 2016,divided into hyperbaric oxygen group(46 cases)and drug group(46 cases)according to the random number table method.The patients in the drug group were given Danzhen headache capsule 3 times a day,hyperbaric oxygen group were treated with Danzhen headache capsule and hyperbaric oxygen.During the treatment,4 cases were deleted in hyperbaric oxygen group and 2 cases in drug group.The clinical effect was evaluated after 18 days,the degree of headache was evaluated by visual analogue scale(VAS)and headache scale(HIT-6)within 24 hours after onset,9 and 18 days after treatment.Results After 18 days of treatment,the total effective rate of hyperbaric oxygen group was higher than that of drug group〔100.0%(44/44)vs 76.2%(32/42)〕(χ~2=11.855,P=0.001).There were significant differences in VAS and HIT-6 scores of the hyperbaric oxygen group and the drug group among within 24 hours of onset and on the 9 th and 18 th day of treatment(P<0.05);VAS and HIT-6 scores on the 9 th and 18 th day of treatment were lower than those within 24 hours,VAS and HIT-6 scores on the 18 th day of treatment were lower than those on the 9 th day(P<0.05).There was no significant difference in VAS and HIT-6 between hyperbaric oxygen group and drug group within 24 hours after onset and on the 18 th day of treatment(P>0.05);on the 9 th day,the VAS and HIT-6 scores of hyperbaric oxygen group were lower than those of drug group(P<0.05).Conclusion Traditional Chinese medicine combined with hyperbaric oxygen in the treatment of patients with acute vascular headache in clinical efficacy is worthy of clinical application.