晚期早产儿室管膜下出血的多因素分析

Multi-factor analysis of subependymal hemorrhage in late preterm infants

【目的】探讨引发晚期早产儿室管膜下出血的相关危险因素,为临床工作中预防和治疗本病提供依据参考。【方法】选取2016年10月至2019年12月本科收治的室管膜下出血的晚期早产儿75例,以同期在院的无颅内出血晚期早产儿作为对照组,采用多因素Logistic回归分析法对11个因素进行研究,分析影响晚期早产儿室管膜下出血的危险因素,并提出防治方法。【结果】多因素分析显示,顺产、妊娠期高血压、新生儿窒息、宫内窘迫为最可能影响并加重晚期早产儿出现室管膜下出血的危险因素。【结论】应加强对胎儿的宫内监测,避免早产,对存在相关高危因素的晚期早产儿进行头颅超声常规筛查,出现室管膜下出血后积极治疗。

【Objective】To explore the risk factors related to subependymal hemorrhage in late preterm infants,and provide reference for the prevention and treatment of this disease in clinic.【Methods】A total of 75 late preterm infants with subependymal hemorrhage treated in our department from October 2016 to December 2019 were selected.The late preterm infants without intracranial hemorrhage during the same period were selected as the control group.Multi-factor logistic regression analysis was used to study 11 factors,analyze the risk factors of subependymal hemorrhage in late preterm infants and put forward prevention and treatment methods.【Results】Multifactor analysis showed that spontaneous delivery,gestational hypertension,asphyxia of newborn and fetal distress were the most likely risk factors affecting and aggravating subependymal hemorrhage in late preterm infants.【Conclusion】Intrauterine monitoring of fetus should be strengthened to avoid preterm birth.Preterm infants with relevant high-risk factors should be screened by head ultrasound and actively treated after subependymal hemorrhage.