阿司匹林联合氯吡格雷对大脑中动脉狭窄脑梗死的疗效

Effect of Aspirin Combined With Clopidogrel in Treating Cerebral Infarction With Middle Cerebral Artery Stenosis

目的探究阿司匹林联合氯吡格雷治疗大脑中动脉狭窄脑梗死的临床效果。方法将58例大脑中动脉狭窄脑梗死患者随机分组,对照组给予阿司匹林治疗,研究组给予阿司匹林联合氯吡格雷治疗,比较两组治疗有效率和1年内的复发率。结果研究组的治疗有效率96.6%高于对照组79.3%(P<0.05)治疗后观察组神经功能缺损程度评分显著低于对照组(P<0.05);观察组1年内研究组复发率0.0%,对照组复发率17.2%,两组比较差异显著(P<0.05)。结论阿司匹林联合氯吡格雷治疗大脑中动脉狭窄脑梗死的疗效显著。

Objective To explore the clinical effect of aspirin combined with clopidogrel on cerebral infarction due to middle cerebral artery stenosis.Methods 58 patients with cerebral infarction with middle cerebral artery stenosis were randomized.The study group received aspirin plus clopidogrel.The effective rate of treatment in both groups and the recurrence rate within 1 year.Results The treatment efficiency of the study group was 96.6%higher than that of the control group was 79.3%(P<0.05).The score of neurological deficit in the observation group was significantly lower than that of the control group(P<0.05).The recurrence rate of the study group was 0.0%within 1 year.The recurrence rate of the control group was 17.2%,and the difference between the two groups was significant(P<0.05).Conclusion Aspirin combined with clopidogrel is effective in the treatment of cerebral infarction of middle cerebral artery stenosis.