球囊子宫支架预防中、重度宫腔粘连术后再复发的临床研究

Clinical Study of Balloon Uterine Stent to Prevent Recurrence After Moderate and Severe Intrauterine Adhesions

目的通过比较分析宫腔粘连术后放置球囊子宫支架+宫内节育器与单一放置宫内节育器的疗效,探讨球囊子宫支架预防宫腔粘连术后再复发的临床价值。方法选取阳江市妇幼保健院2017年10月—2019年9月收治的中、重度宫腔粘连患者87例,随机分为观察组和对照组,观察组42例,对照组45例。观察组宫腔粘连分离术后采取放置球囊子宫支架+宫内节育器,对照组术后采取单一放置宫内节育器。两组均术后予雌孕激素作人工周期治疗3个月。结果87例患者治疗均获得不同程度成功。观察组术后48小时出血量明显少于对照组,差异有显著统计学意义(P<0.01)。观察组有效率95.2%(40/42),治愈率59.5%(25/42);对照组有效率75.6%(34/45),治愈率35.6%(16/45),两者相比,差异有统计学意义(P<0.05)。两者的术后感染率比较差异无统计学意义(P>0.05)。结论球囊子宫支架可有效预防中、重度宫腔粘连分离术后再复发。

Objective To explore the clinical value of balloon uterine stent in preventing recurrence after intrauterine adhesions by comparing the efficacy of balloon uterine stent+intrauterine device and single intrauterine device after intrauterine adhesion.Methods 87 patients with moderate and severe intrauterine adhesions treated in Yangjiang Maternal and Child Health Hospital from October 2017 to September 2019 were selected,and they were randomly divided into the observation group(n=42)and the control group(n=45).A balloon uterine stent and an intrauterine device were placed in the observation group after separation of the intrauterine adhesions,and a single intrauterine device was placed in the control group after the operation.Both groups were treated with estrogen and progestin for 3 months after artificial cycle.Results All 87 patients were successfully treated to varying degrees.The 48-hour postoperative bleeding volume in the observation group was significantly less than that in the control group,and the difference was statistically significant(P<0.01).The effective rate in the observation group was 95.2%(40/42)and the cure rate was 59.5%(25/42).The effective rate in the control group was 75.6%(34/45)and the cure rate was 35.6%(16/45).The difference was statistically significant(P<0.05).There was no statistically significant difference in postoperative infection rates between the two(P>0.05).Conclusion The balloon uterine stent can effectively prevent recurrence after separation of moderate and severe uterine adhesions.