蓝光照射联合磺胺嘧啶银脂质水胶敷料治疗PICC导管局部感染的效果

Effect of blue light irradiation and sulfadiazine silver lipid water gel dressing in the treatment of local infections of PICC catheters

目的 探讨蓝光照射联合磺胺嘧啶银脂质水胶敷料治疗PICC导管局部感染的效果。方法 选择2016-10至2018-08解放军总医院PICC门诊PICC置管后出现局部感染59例,按照随机数字表法分为对照组(29例)和试验组(30例),一个疗程为7 d,第1、2、3天对照组单纯使用磺胺嘧啶银敷料,而试验组使用磺胺嘧啶银敷料结合蓝光照射,第5天和第7天两组均只进行敷料换药,在治疗的第1、3、5、7天分别观察两组伤口疼痛评分(NRS),治疗后第7天观察创面愈合疗效。结果 与对照组相比,治疗第1天试验组即能显著减轻伤口疼痛,差异有统计学意义(Z=-2. 30,P <0. 05)。其中创面愈合情况痊愈+显效两组比较,试验组明显优于对照组(χ^2=7. 81,P=0. 04)。结论 试验组通过增加蓝光照射,比单纯使用磺胺嘧啶银敷料治疗能快速减轻疼痛、提高创面愈合的疗效。

Objective To investigate the therapeutic effect of blue light irradiation and sulfadiazine silver lipid water gel dressing against PICC placement related local infections.Methods Using the random stratification method,a total of 59 patients with local infections after PICC placement were divided into two groups:the control group(29 cases)and the experimental group(30 cases).One course of treatment lasted 7 days.On the 1st,2nd and 3rd days,patients in the control group received dressing treatment only,whereas patients in experimental group received dressing and blue light treatment.On the 5th and 7th days,patients in both groups received dressing treatment.The pain scores(NRS)were measured on the 1st,3rd,5th and 7th days.The wound healing effect was observed on the 7th day.Results Compared with the control group,the wound pain in the dressing/blue-light treatment group was significantly reduced on the 1st day,and the difference was statistically significant(Z=-2.30,P<0.05).Significant differences were also observed between the two groups in the cure and excellent rate of wound healing(χ^2=7.81,P=0.04)which indicated that the dressing/blue-light combined therapy was more effective than the dressing therapy in assisting the healing of wounds.Conclusions Compared with the control group,the dressing/blue-light treatment group can quickly relieve pain and improve the curative effect of wound healing.