基于“脾气散精”探讨Ghrelin对糖尿病并发症的影响

The Influence of Ghrelin on Complications of diabetes Based on"Spleen Dispersing Essence"

“脾气散精”是中医理论对脾生理功能的高度概括。现代医学发现“脾气散精”与人体的糖脂代谢密切相关。“脾不散精”会导致水谷精微布散出现异常,进而出现消渴及兼症。脾气散精与Ghrelin的能量平衡调控作用有相似之处。笔者试着总结概述“脾气散精”与Ghrelin对能量平衡的调控探讨对糖尿病并发症影响的相关性,以便阐述通过恢复脾气散精调控Ghrelin以治疗糖尿病并发症的可能,为临床防治糖尿病及其并发症提供新思路。

"Spleen dispersing essence"is a highly summarized theory of traditional Chinese medicine on the physiological function of the spleen.Modern medicine has found that"spleen dispersing essence"is closely related to the body's glucose and lipid metabolism.The phenomenon of"spleen not dispersing essence"can lead to abnormal distribution of water grain essence,leading to diabetes and concurrent symptoms.There are similarities in the regulation of energy balance between“spleen dispersing essence”and Ghrelin.The author tries to summarize and summarize the regulation of"spleen dispersing essence"and Ghrelin on energy balance and explore the correlation of their impact on diabetes complications,so as to elaborate the possibility of regulating Ghrelin to treat diabetes complications by restoring spleen dispersing essence,and provide new ideas for clinical prevention and treatment of diabetes and its complications.