川崎病并发冠脉损伤的高危因素及不典型川崎病早期诊断的研究进展

RESEARCH PROGRESS IN HIGH RISK FACTORS OF KAWASAKI DISEASE COMPLICATED WITH CORONARY ARTERY INJURY AND EARLY DIAGNOSIS OF ATYPICAL KAWASAKI DISEASE

川崎病是一种由超抗原触发的以全身中小血管非特异性炎性反应为主要病理改变的免疫系统疾病,又称皮肤黏膜淋巴结综合征。近年来,川崎病的发病率在世界各国均逐年上升,同时合并有冠状动脉损伤及不典型川崎病的患儿日益增多,严重影响患儿的生活质量。基于此,本文就关于川崎病并发冠状动脉损伤的高危因素及不典型川崎病早期诊断的相关进展做一综述,以期为临床诊断提供一定的参考价值。

Kawasaki disease is a kind of immune system disease triggered by superantigen,which is mainly caused by non-specific inflammatory reaction of small and medium blood vessels in the whole body.It is also called mucocutaneouslymphnodesyndrome.In recent years,the incidence of Kawasaki disease has increased year by year in all countries of the world,and the number of children with coronary artery injury and atypical Kawasaki disease is increasing,which seriously affects the quality of life of children.Based on this,this article reviews the high-risk factors of Kawasaki disease complicated with coronary artery injury and the related progress of early diagnosis of atypical Kawasaki disease,in order to provide a certain reference value for clinical diagnosis.