韩捷从浊毒论治溃疡性结肠炎及肠外表现经验

Experience on HAN Jie Treating Ulcerative Colitis and Its Extra-intestinal Manifestations from Turbid Toxin

介绍韩捷教授从浊毒论治溃疡性结肠炎及肠外表现的经验。溃疡性结肠炎是一种慢性非特异性炎症性肠病,受饮食环境等多种因素的影响,溃疡性结肠炎的发病率越来越高,病情难以控制、容易复发,并伴有多种肠外表现。韩捷教授长期从事溃疡性结肠炎的治疗与研究,将其分为大肠湿热、脾虚湿热、脾肾亏虚3种证型,并与浊毒理论相结合,提出湿热内蕴化生浊毒、脾虚湿热兼有浊毒、脾肾亏虚浊毒胶结的观点。韩捷教授认为,浊毒既能从外而入,又可由内而生,致病十分广泛,溃疡性结肠炎伴有的口腔溃疡,结节性红斑,外周关节炎等肠外表现均可从浊毒论治,在治疗溃疡性结肠炎的基础上,分别加用清热滋阴化浊、凉血化瘀解毒、化浊通络止痛的药物来治疗其肠外表现。临床上采用中药口服、七炭方灌肠、健脾栓纳肛、中医外治4种手段,把祛湿化浊解毒贯穿其中,提供了一种新的治疗思路,临床上取得了一定疗效。

The experience of professor HAN Jie treating ulcerative colitis(UC)and extra-intestinal manifestations from turbid toxin was introduced.UC is a chronic nonspecific inflammatory bowel disease.Affected by various factors,such as dietary environment,the incidence of UC is increasing,symptoms are difficult to control and easy to relapse,accompanied by a variety of extraintestinal manifestations.Professor HAN Jie has been engaged in the treatment and research of UC for a long time.He divides UC into three syndrome types:large intestinal dampness-heat syndrome,syndrome of dampness-heat due to spleen deficiency,spleen-kidney deficiency syndrome.Combined with the theory of turbid toxin,this paper puts forward the view of dampness-heat internal accumulation generating turbid toxin,spleen deficiency with dampness-heat and turbid toxin,spleen and kidney deficiency with turbid toxin cementation.Professor HAN Jie believes that turbid toxin can not only enter from the outside,but also from the inside,causing a wide range of diseases.UC is accompanied by oral ulcers,erythema nodosum,peripheral arthritis and other parenteral manifestations which can be treated from turbidity toxin.On the basis of the treatment of UC,drugs for clearing heat and nourishing Yin and removing turbidity,cooling blood and removing blood stasis and detoxification,and removing turbidity and collaterals to relieve pain are added to treat its parenteral manifestations.The clinical use four means including oral Chinese medicine,seven carbonized drugs-retention enema,anus with fortifying spleen suppository and external treatment of traditional Chinese medicine,can remove dampness and eliminateturbid and resolve toxin throughout the whole process,providing a new treatment idea and the treatment methods have achieved certain clinical effect.