基于“络病理论”从瘀毒论血脂异常

Discussion on Dyslipidemia from Blood Stasis and Toxin Based on Theory of Collateral Disease

"络病理论"源于《黄帝内经》,是指导中医诊疗疾病的重要理论之一。血脂异常是一种血液代谢性疾病,近年来其发病率呈现上升趋势,但其发病机制尚未完全明确。文章基于"络病理论"来进一步探讨血脂异常的发病机制及治法,通过"络病理论"及瘀毒的致病特点,分析瘀毒与血脂异常发病的关系,进而阐释瘀毒阻络、毒伤络脉、络脉虚损导致血脂异常的发病机制。认为络脉作为聚血之所,是血液循环的重要通道,血液的正常运行与其密切相关,由于络脉管腔狭窄,且位于表里营卫之间,外邪易于侵袭,容易产生瘀血,瘀血阻络日久化毒,瘀毒胶着滞于络脉,损伤脉体,可致络脉虚损,进而发为血脂异常。治疗上结合络脉"络以通为用"的治疗原则以及治瘀、治毒之法则,并分析现代科学研究的成果,认为治疗血脂异常宜采用活血化瘀、祛毒通络之法,以期为血脂异常的中医诊疗提供理论参考及研究方向。

“Collateral disease theory”is originated from Huangdi Neijing,which is one of the important theories to guide the diagnosis and treatment of diseases in traditional Chinese medicine.Dyslipidemia is a metabolic disease of blood.Its incidence rate has been increasing in recent years,but its pathogenesis is not yet clear.Based on the theory of collateral disease,this paper further discussed the pathogenesis and treatment of dyslipidemia.Through the theory of collateral disease and the pathogenic characteristics of blood stasis and toxin,the relationship between blood stasis and dyslipidemia was analyzed,and then the pathogenesis of dyslipidemia caused by blood stasis and toxin blocking collaterals,toxin injuring collaterals and collateral deficiency damage was explained.It is considered that collaterals are important channels of blood circulation,and the normal operation of blood is closely related to it.Due to the narrow lumen of collaterals,which is located between the exterior and interior,Ying and Wei,external pathogenic factors are easy to invade and easily produce blood stasis.Blood stasis can block collaterals for a long time and turn into toxin.Blood stasis and toxin stick to collaterals and damage the blood vessels,which can lead to deficiency of collaterals and then lead to dyslipidemia.According to the treatment principle of collaterals and the principle of treating blood stasis and toxin,and analyzing the results of modern scientific research,it is suggested that the method of promoting blood circulation and removing blood stasis,removing toxin and unblocking collaterals should be adopted in the treatment of dyslipidemia,so as to provide theoretical reference and research direction for TCM diagnosis and treatment of dyslipidemia.