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Pathogenesis of Cerebral Ischemia Based on brain-heart interaction

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摘要 Over the last few years,neuro-cardiology has grown the awareness of the relationship between the brain and the heart,contributing to developing a modern interdisciplinary field of neuro-cardiology.To enhance the awareness of the relationship between the brain and the heart,we concentrate on the brain function disability that results from cardiac dysfunction and the brain function impairment that results from cardiac dysfunction.It is usual for patients with cerebral ischemia to be preceded by cardiac impairment.The main triggers of cerebral ischemia involve arrhythmia,atrial fibrillation,etc.,reflecting a strong connection between the heart and the brain.Cerebral ischemia is linked to how the heart and brain communicate and affect each other at the pathophysiological stage.The formation of the heart-brain axis mechanism is important in its incidence and growth.The analysis explores the etiology and pathogenesis of cerebral ischemia centered on the heart-brain axis neuronal pathway and the mechanism of the relationship between the heart and brain,which offers important enrichment to the hypothesis of combined care of brain and heart and is extremely useful for gaining new knowledge for research and production of multi-target drugs for the prevention and treatment of cerebral ischemia.
作者 于长江 邓刚 Muqaddas Masood 欧阳情 何茵茹 陈寄梅 朱平 Moussa Ide Nasser YU Chang-jiang;Deng Gang;Muqaddas Masood;OUYANG Qing;HE Yin-ru;CHEN Ji-mei;ZHU Ping;Moussa Ide Nasser(Guangdong Cardiovascular Institute,Guangdong Provincial People's Hospital,Guangdong Academy of Medical Sciences,Guangzhou,Zhongshan Road,Guangzhou,PR China,510080;Guangdong Provincial Key Laboratory of Pathogenesis,Targeted Prevention and Treatment of Heart Disease,Add:106 Zhongshan Er Road,Guangzhou,PR China,510080)
出处 《South China Journal of Cardiology》 CAS 2022年第2期129-141,152,共14页 岭南心血管病杂志(英文版)
基金 supported by NSFC Projects of International Cooperation and Exchanges(NO.81720108004) National Natural Science Foundation of China(NO.81974019) The Research Team Project of Natural Science Foundation of Guangdong Province of China(NO.2017A030312007) Science and Technology Planning Project of Guangdong Province(NO.2022B1212010010) The key program of guangzhou science research plan(NO.201904020047) The Special Project of Dengfeng Program of Guangdong Provincial People’s Hospital(NO.DFJH201812 NO.KJ012019119 NO.KJ012019423.)
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