摘要
Coronary atherosclerotic heart disease had been regarded as the leading killer of human being.The atherosclerotic lesion would cause blood flow blockage or lumen stenosis of coronary arteries,thus resulting in myocardial ischemic or sudden cardiac death.Though exact causes of coronary atherosclerosis heart disease is not known,the promising Apo C-Ⅲthat played a crucial role in metabolism of triglyceride-rich lipoproteins had been supposed to be one of the key factor of pathogenesis.In this review,we discuss roles of Apo C-Ⅲin the development of CAD and its insights being a new therapeutic target.
作者
玉今珒
朱平
潘微
YU Jin-jin;ZHU Ping;PAN Wei(Department of Cardiac Surgery,Guangdong Cardiovascular Institute,Guangdong Provincial People's Hospital,Guangdong Academy of Medical Sciences;Department of Pediatric Cardiology,Guangdong Cardiovascular Institute,Guangdong Provincial People's Hospital,Guangdong Academy of Medical Sciences;Department of Maternal-Fetal Cardiology,Guangdong Cardiovascular Institute,Guangdong Provincial People's Hospital,GuangdongAcademy of Medical Sciences)