泛影葡胺注射治疗老年乳腺癌改良根治术后腋窝积液疗效分析

Efficacy of meglumine diatrizoate injection in the treatment of elderly patients with axillary effusion after modified radical mastectomy

目的探讨泛影葡胺局部注射联合上肢弹力绷带包扎法治疗老年乳腺癌改良根治术后腋窝积液的效果。方法选取2017年1月至2019年6月滨州医学院烟台附属医院收治的老年乳腺癌改良根治术后腋窝积液患者68例,其中34例(观察组)行泛影葡胺局部注射联合上肢弹力绷带包扎法+负压引流并局部加压包扎治疗,34例(对照组)行单纯负压引流并局部加压包扎治疗。比较两组患者腋窝引流量、腋窝引流管留置时间及不良反应的发生情况。组间比较采用t检验。结果观察组腋窝引流量明显低于对照组,腋窝引流管留置时间明显少于对照组,差异均有统计学意义(t=1.489、5.831,P<0.05或0.01)。两组患者均无全身不良反应发生。结论泛影葡胺局部注射联合上肢弹力绷带包扎法可明显减少腋窝引流量、显著缩短腋窝引流管留置时间,简便易行、安全性高。

Objective To investigate the effect of meglumine diatrizoate local injection combined with upper limb elastic bandage in the treatment of elderly patients with axillary effusion after modified radical mastectomy.Methods 68 elderly patients with axillary effusion after modified radical resection of breast cancer admitted to the Yantai Affiliated Hospital of Binzhou Medical College from January 2017 to June 2019 were selected.Among them,34 patients(observation group)received local injection of methylene blue combined with upper limb elastic bandage+negative pressure drainage and local pressure dressing,while 34 patients(control group)received simple negative pressure drainage and local pressure dressing.The axillary drainage volume,indwelling time of axillary drainage tube and the occurrence of adverse reactions were compared between the two groups.T test was used for comparison between groups.Results The axillary drainage volume of the observation group was significantly lower than that of the control group,and the indwelling time of the axillary drainage tube was significantly lower than that of the control group(t=1.489,5.831;P<0.05 or 0.01).No systemic adverse reactions occurred in both groups.Conclusion Local injection of meglumine diatrizoate combined with upper limb elastic bandage bandage can significantly reduce axillary drainage volume and significantly shorten the indwelling time of axillary drainage tube,which is easy to operate and has high safety.