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《阿托伐他汀能够改善激素耐药型免疫性血小板减少患者的骨髓血管内皮细胞功能》解读 被引量:3

Comments on "Atorvastatin enhances bone marrow endothelial cell function in corticosteroid-resistant immune thrombocytopenia patients"
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摘要 本文最初作为封面焦点文章发表于2018年Blood杂志上,Blood杂志当期配发专家述评。文章题录为:Kong Y,Cao XN,Zhang XH,et al.Atorvastatin enhances bone marrow endothelial cell function in corticosteroid-resistant immune thrombocytopenia patients[J].Blood,2018,131:1219-1233.文章采用前瞻性配对临床队列研究,首次从骨髓血管内皮细胞角度揭示了激素耐药型免疫性血小板减少的全新发病机制及其临床干预策略,有望为建立激素耐药型免疫性血小板减少患者的新型防治体系奠定理论基础。经通信作者许可,再次通过佳文解读的方式来阐述这一发现。
作者 孔圆 黄晓军
出处 《临床血液学杂志》 CAS 2020年第1期1-5,共5页 Journal of Clinical Hematology
基金 国家自然科学基金项目(No:81530046、81870139).
关键词 激素耐药型免疫性血小板减少 骨髓血管内皮细胞 阿托伐他汀 活性氧 乙酰半胱氨酸 corticosteroid-resistant immune thrombocytopenia bone marrow endothelial cells atorvastatin re-active oxygen species N-acetyl-L-cysteine
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  • 1ProvanD, StasiR, NewlandAC, et al. International consensus report on the investigation and management of primary immune thrombocytopenia[J]. Blood,2010,115(2):168-186.
  • 2NeunertC, LimW, CrowtherM, et al. The American Society of Hematology 2011 evidence-based practice guideline for immune thrombocytopenia[J]. Blood,2011,117(16):4190-4207.
  • 3British Committee for Standards in Haematology General Haematology Task Force. Guidelines for the investigation and management of idiopathic thrombocytopenic purpura in adults, children and in pregnancy[J]. Br J Haematol,2003,120(4):574-596. doi:10.1046/j.1365-2141.2003.04131.x.
  • 4WeiY, JiXB, WangYW, et al. High-dose dexamethasone versus prednisone for treatment of adult immune thrombocytopenia: a prospective multicenter randomized trial[J]. Blood,2016,127(3):296-302. doi:10.1182/blood-2015-07-659656.
  • 5WangS, YangR, ZouP, et al. A multicenter randomized controlled trial of recombinant human thrombopoietin treatment in patients with primary immune thrombocytopenia[J]. Int J Hematol,2012,96(2):222-228. doi:10.1007/s12185-012-1124-8.
  • 6BusselJB, ChengG, SalehMN, et al. Eltrombopag for the treatment of chronic idiopathic thrombocytopenic purpura[J]. N Engl J Med,2007,357(22):2237-2247. doi:10.1056/NEJMoa073275.
  • 7BusselJB, ProvanD, ShamsiT, et al. Effect of eltrombopag on platelet counts and bleeding during treatment of chronic idiopathic thrombocytopenic purpura: a randomised, doubleblind, placebo-controlled trial[J]. Lancet,2009,373(9664):641-648. doi:10.1016/S0140-6736(09)60402-5.
  • 8ChengG, SalehMN, MarcherC, et al. Eltrombopag for management of chronic immune thrombocytopenia (RAISE): a 6-month, randomised, phase 3 study[J]. Lancet,2011,377(9763):393-402. doi:10.1016/S0140-6736(10)60959-2.
  • 9SalehMN, BusselJB, ChengG, et al. Safety and efficacy of eltrombopag for treatment of chronic immune thrombocytopenia: results of the long-term, open-label EXTEND study[J]. Blood,2013,121(3):537-545. doi:10.1182/blood-2012-04-425512.
  • 10KuterDJ, BusselJB, LyonsRM, et al. Efficacy of romiplostim in patients with chronic immune thrombocytopenic purpura: a double-blind randomised controlled trial[J]. Lancet,2008,371(9610):395-403. doi:10.1016/S0140-6736(08)60203-2.

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