心外膜脂肪组织、肥胖与心房颤动的研究进展

Advances in research on the role of epicardial adipose tissue and obesity in atrial fibrillation

心外膜脂肪组织是一种靠近心脏的活性内脏脂肪组织,已被证明是心房颤动的危险因素。大量研究表明,随着心外膜脂肪组织厚度和体积的增加,心房颤动的发病率和复发率逐渐增加;流行病学研究亦证实了肥胖在心房颤动发生和发展中的作用。本文就心外膜脂肪组织与肥胖在心房颤动发生和维持中的作用机制及新进展作一综述。

Epicentral adipose tissue(EAT)is an active visceral adipose tissue close to the heart that has been shown to be a risk factor for atrial fibrillation.Numerous studies have shown that with the increase in thickness and volume of EAT,the incidence and recurrence rate of atrial fibrillation gradually increase.Epidemiological studies have also confirmed the role of obesity in the occurrence and development of atrial fibrillation.This article reviews the mechanism and new progress of EAT and obesity in the occurrence and maintenance of atrial fibrillation.