微量元素改性PEEK种植体的研究进展

Research progress on trace elements modification of PEEK implant

聚醚醚酮(polyetheretherketone,PEEK)是一种高性能特种塑料,它的力学性能和生物相容性较好,且易于加工成型,已成为牙科种植体的备选材料。PEEK由于缺乏生物活性以及易导致菌斑聚集,限制了其在口腔种植领域的临床应用。目前很多学者通过微量元素改性的方法解决了PEEK的生物惰性和菌斑附着问题。不同微量元素各具优势,锶、钽、锰等元素可以促进成骨细胞分化,氟、银、锌等元素则可以抑制致炎细菌生长,多种微量元素共修饰赋予PEEK种植体更为多元化的性能。

Polyetheretherketone(PEEK)is a high-performance specialty plastic with good mechanical properties and biocompatibility and is easy to process and form,making it an alternative material for dental implants.However,the lack of biological activity and the easy accumulation of plaque limit the clinical application of PEEK in the field of oral implantology.At present,many scholars solve the problem of biological inertia and plaque attachment of PEEK through trace elements modification.Different trace elements have their own advantages.Strontium,tantalum,manganese,and other elements can promote osteoblast differentiation.Fluorine,silver,zinc,and other elements can inhibit the growth of inflammatory bacteria,and the co-modification of various trace elements gives PEEK implant more diversified properties.