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质子泵抑制剂对经皮冠状动脉介入治疗术后上消化道出血影响分析 被引量:6

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摘要 目的探讨质子泵抑制剂对经皮冠状动脉介入治疗术后服用双联抗血小板药物预防上消化道出血的临床疗效。方法选取自2018年6月至2019年12月火箭军特色医学中心收治的100例行经皮冠状动脉介入治疗的冠心病患者为研究对象。采用随机数字表法将其分为A组与B组,每组各50例。A组患者服用阿司匹林与氯吡格雷。B组患者在A组基础上,口服埃索美拉唑镁肠溶片。记录并比较两组患者上消化道出血及不良心脑血管事件发生率。结果两组心脑血管不良事件发生率比较,差异无统计学意义(P>0.05)。B组患者上消化道出血发生率为4.0%(2/50),显著低于A组的22.0%(11/50),差异有统计学意义(P<0.05)。结论冠心病患者经皮冠状动脉介入治疗术前、术后使用质子泵抑制剂并未增加心脑血管不良事件发生,反而会降低双联抗血小板治疗所致消化道出血发生率。
出处 《临床军医杂志》 CAS 2020年第10期1246-1247,共2页 Clinical Journal of Medical Officers
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