大鼠缰核的传入投射——WGA-HRP法研究

THE AFFERENT PROJECTIONS OF THE HABENULAR NUCLEI IN THE RAT——A WGA-HRP STUDY

将WGA-HRP微电泳于40只大鼠缰核的不同部位,观察其逆行标记细胞分布和将WGA-HRP微电泳于12只大鼠的脚内核、视前区、伞隔核和三角隔核、斜角带核及丘脑下部外侧区等处观察顺行标记终支在缰核中的分布。缰核不同部位的传入来源不同,外侧缰核主要接受脚内核、外侧视前区、斜角带核及丘脑下部外侧区等的传入,可能和纹状体及边缘系统功能有关。内侧缰核主要接受隔核的传入,可能和边缘系统功能有关。外侧缰核还可再分为内侧、外侧两部,内侧缰核也可再分为内侧及外侧两部,它们各接受不同的传入,并可能具有不同的功能。

WGA-HRP was iontophoretically delivered into the habenular nuclei in 40 rats to observe the distribution of the retrograde labeled cells;and into the entopeduncular nucleus(EPN),lateral preoptic area(LPO),medial preoptic area(MPO),nucleus septalis fimbriatis(SF),nucleus triangularis septi(TS),nucleus tractus diagonalis(Broca)(DBN)and lateral hypothalamic area(LHA)in 12 rats to observe the distribution of the orthograde labeled fibers in the habenular nuclei.It was found that the afferents of various parts of the habenular nuclei were different.The lateral habenular nucleus mainly recieves the afferents from the EPN,LPO and LHA,and the medial habenular nucleus from the SF,TS and LHA.Furthermore,the lateral habenular nucleus can be divided into medial and lateral parts,the medial habenular nucleus can be divided into medial and lateral parts as well,their afferent connections are also different.