金黄地鼠上丘和外侧膝状体之间的联系

CONNECTION BETWEEN THE SUPERIORCOLLICULUS AND LATERAL GENICULATE BODY IN THE GOLDEN HAMSTER

本实验采用了顺行和逆行追踪技术,对金黄地鼠上丘与丘脑视核团的纤维联系进行了实验观察。一、用尼氏和Loyez染色法,对4只正常金黄地鼠上丘和外侧膝状体背核和腹核的正常结构做了观察。二、^(3)H-亮氨酸和^(3)H-脯氨酸注入动物上丘不同部位(4只,存活期一天)后,可见神经末梢标记于同侧的外侧膝状体背核和腹核的外侧部位。若注射部位在上丘外侧,其投射部位在外侧膝状体背核和腹核的尾外侧;注射部位移向内侧,投射部位移向吻外侧。三、将HRP注入外侧膝状体背核(4只,存活期一天)或腹核(2只,存活期一天)或后外侧核(2只,存活期一天)后,在同侧上丘浅层见有标记神经元。在上丘深层则未见。本实验说明了上丘浅层的神经元对同侧的外侧膝状体背核和腹核有局部定位的投射,并按视野和视网膜将该投射作定位排列。

Connection between the superior colliculus(SC)and the dorsal and ventral lateral geniculate nuclei(LGd and LGv)were studied in adult golden hamsters using anterograde and retrograde pathway tracing methods 1.In four hamsters,the cytoarchitecture of the SC,LGd and LGv was examined in brain sections stained with Nissl’s or Loyez’s method.2.A single injection of a mixture of^(3)H-leucine and^(3)H-proline was made into various regions of the SC in each of 4 animals(1 day survival)for studying the pattern of terminal distribution of the projections from the SC to the ipsilateral LGd and LGv.In animals where the injection site was located in the superficial gray layers of the lateral portion of the SC,labelled terminals were found in the caudal lateral part of the LGd and LGv.In the case where the injection was restricted in more medial part of the SC,the terminal labelling was observed in the rostral lateral portion of the lateral geniculate nuclei.3.One day after an injection of horseradish peroxidase(HRP)into the LGd(4 animals),LGv(2 animals),or LP(2 animals)labelled neurons were observed in the superficial gray layers of the ipsilateral superior colliculus.No HRP-labelled neuron was detected in deeper laminae in the colliculus.These results indicate that neurons in the superficial gray layers of the SC project to the ipsilateral LGd and LGv,and the projections are organized topogra-phically according to the retinotopic or visual field map.