大白鼠视前区的传入联系——HRP法研究

AFFERENT CONNECTIONS OF THE PREOPTIC REGION——STUDIED WITH HRP METHOD IN THE RAT

本实验应用HRP微电泳法研究了大白鼠视前大细胞核、视前外侧核和视前内侧核的传人纤维来源。结果表明,视前大细胞核主要接受边缘系(特别是嗅脑)的纤维投射;视前内侧核主要接受下丘脑内侧区某些与垂体功能密切相关的核团和杏仁体的投射;而视前外侧核则具有来自脑的各平面某些结构和少量上段颈髓的传入纤维,其中以脑干部分为主。此外,本实验发现视前外侧核和视前大细胞核均接受额前皮质的纤维传入并具有定位关系,视前内侧核背侧份可能具有该核腹侧份所没有的某些低位脑干结构的传入纤维。本文还对上述各核的传入联系上的差异与功能上的可能关系进行了初步探讨。

The afferent connections of the magnocellular preoptic(poma),lateral preoptic(pol),and medial preoptic(pom)nuclei have been investigated with horseradish peroxidase(HRP)method in the rat.Our findings indicated that 1.poma mainly receives projection from the rhinencephalic structures including the anterior olfactory nucleus,olfactory tubercle,piriform cortex,entorhinal cortex,the nucleus of lateral olfactory tract,the anterior amygdaloid area,and the cortical amygdaloid nucleus;2.pom mainly receives afferent fibers from some of the medial hypothalamic nuclei;3.pol has the most extensive fiber input,mainly from some of the brain stem nuclei;and 4.poma is the only one of the preoptic nuclei which has reciprocal connections with the contralateral forebrain structrues.It is interesting that the poma and pol receive the afferent fibers from different prefrontal cortical regions and the dorsal portion of pom may have input from the lateral reticular nucleus and nucleus tractus solitarii that the ventral portion may not have.In addition,a large number of HRP-labeled cells could be seen in the supraoptic nucleus after injecting any one of the preoptic nuclei and the possible signification was discussed.