二氧化碳激光所作皮肤切口愈合过程的组织学观察

HISTOLOGICAL OBSERVATIONS ON THE HEALING PROCESS OF SKIN INCISIONS BY CARBON DIOXIDE LASER

1.豚鼠皮肤用二氧化碳激光切口比手术刀切口愈合期显著延迟,瘢痕也大。2.激光使切口周围组织热凝固,由此产生不出血作用。3.激光切口愈合过程中所见到的肥大细胞数量多于手术刀组的五倍,是否与机体的修复和防御有关,有待进一步研究。4.用0.1%新洁尔灭清除焦化组织后,可能有防止感染和加速愈合的作用。

Eight healthy male adult guinea pigs were divided into four groups.Skin incisions were made on each Side of the back of each with COlaser and scalpel respectively,and were sutured.Post-operative samples were taken on the 3rd,5th,7th and 14th days,and histological preparations were studied.The results were as follows:1.The healing process of COlaser incisions were obviously retarded in comparison with those of scalpel,and usually produced a bigger scar.2.Laser caused the tisues of the cutting edges to coagulate,thus produced a sort of haemostasis.3.In laser incisions there were almost five times as many of mast cells being observed during the healing process than those by scalpel.It needs further studies to make sure whether it is related to the repair and defence of organism.4.Gleaned up the burnt tissues with 0.1%Benzalkonium bromide seemed to have the effect of preventing infection and accelerating the healing process.