抑郁障碍患者正念认知疗法干预后生活质量病例对照研究

Case-control study on quality of life in patients with depression after mindfulness cognitive therapy intervention

目的:研究正念认知疗法干预对抑郁障碍患者生活质量的影响。方法:将60例抑郁障碍患者分两组,对照组进行药物治疗,研究组在药物治疗的同时进行正念认知疗法干预等心理康复干预。分别用汉密尔顿抑郁量表17版本(HAMD-17)、五因素正念评估量表(FFMQ)、生活质量问卷(SF-12)对干预后两组患者精神状态、正念水平及生活质量进行评定和比较。结果:为期8周正念认知疗法干预后,研究组HAMD-17评分明显低于对照组(t=-2.423,P<0.05),研究组在观察、有觉知行动、不判断、不反应维度和总分评分上高于对照组(t=4.214,3.098,3.358,2.410,3.389;P<0.05);研究组SF-12生理及心理总评分显著高于对照组,有统计学意义(t=2.062,3.769;P<0.05)。结论:正念认知疗法干预能够很好地促进患者管理自己情绪,改善家庭与社会功能,显著降低复发率、提高患者正念水平和生活质量。

Objective:To study the effect of mindfulness cognitive therapy on the quality of life of patients with depression.Methods:Sixty patients with depressive disorder were divided into two groups.The control group was treated with drugs,while the research group was treated with psychological rehabilitation intervention such as mindfulness cognitive therapy.Hamilton Depression Scale 17(HAMD-17),Five-factor Mindfulness Assessment Questionnaire(FFMQ)and Quality of Life Questionnaire(SF-12)were used to evaluate and compare the mental status,mindfulness level and quality of life of the two groups after intervention.Results:After 12 weeks of mindfulness cognitive therapy intervention,the HAMD-17 score of the study group was significantly lower than that of the control group(t=-2.423,P<0.05).The FFMQ observation,acting with awareness,non-judging,non-reacting and total score of the study group were higher than those of the control group(t=4.214,3.098,3.358,2.410,3.389;P<0.05).The physical and psychological total scores of SF-12 in the study group were significantly higher than those in the control group(t=2.062,3.769;P<0.05).Conclusion:Mindfulness cognitive therapy intervention can promote patients to manage their emotions,improve family and social functions,significantly reduce the recurrence rate,improve patients’mindfulness level and quality of life.