摘要
随着全球数据量爆炸式增长,传统的数据存储介质面临极大挑战.DNA凭借其存储密度高、可长期保存等优点,成为很有潜力的新型数据存储介质.数字影音档案数据量大,要求保存时间久,适合使用DNA作为存储介质.本文以存储历史影音档案文件为例,编码合成了272340条、长度为169碱基的寡核苷酸,存储数据量超过3.0MB,包括两段音视频片段与一份中文文本;设计了融合寡核苷酸合成池、扩增引物、数据块、不同文件等要素的多层次读取方法.设计的编码处理与读取方法实现了面向DNA介质的高密度存储.
With the explosive growth of the global data volume,traditional storage media have faced great challenge in satisfying the increasing storage requirement.Deoxyribonucleic acid(DNA)has become a new storage medium with great potential due to its ultra-high storage density and ultra-long storage durability.DNA may serve as the most suitable medium for digital archives of audio and video(AV)files because of its large storage volume and long durability.In this paper,we stored historical AV files to show the storage pottial of DNA media.We encoded two AV clips and a Chinese text with the overall volume larger than 3.0 MB into pooled 272340 oligos with a length of 169 nt.Simultaneously,we presented a hierarchical flexible access scheme integrating different synthesis pool,primers,data block and files.The proposed encoding and access method verifies the ultra-high density storage using synthetic pools.
作者
陈为刚
黄刚
李炳志
尹烨
元英进
CHEN WeiGang;HUANG Gang;LI BingZhi;YIN Ye;YUAN YingJin(School of Microelectronics,Tianjin University,Tianjin 300072,China;School of Chemical Engineering and Technology,Tianjin University,Tianjin 300072,China;Frontiers Science Center for Synthetic Biology(MOE),Tianjin University,Tianjin 300072,China;BGI Genomics,Shenzhen 518000,China)
出处
《中国科学:生命科学》
CSCD
北大核心
2020年第1期81-85,共5页
Scientia Sinica(Vitae)
基金
国家自然科学基金(批准号:21621004,21750001)
天津大学自主创新基金资助.
关键词
数据存储
DNA信息存储
合成寡核苷酸池
data storage
DNA information storage
synthetic oligonucleotide(oligo)pool