PTED与FD治疗腰椎间盘突出症的效果比较

Comparison of clinical effect of percutaneous transforaminal endoscopic discectomy and fenestration discectomy on the lumbar disc herniation

为探讨经皮椎间孔镜椎间盘切除术(PTED)和椎板开窗椎间盘切除术(FD)在腰椎间盘突出症(LDH)患者治疗中的临床效果差异。94例LDH患者,根据手术方法分为PTED组和FD组各47例。结果表明,与FD组相比,PTED组的手术切口长度、手术出血量、住院时间降低,术后7天,血清白细胞介素-1β(IL-1β)、白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)、前列腺素-E2(PGE2)水平也显著降低;与术前比较,术后3个月、术后6个月,两组患者的ODI指数均显著降低。结果说明,PTED与FD治疗LDH患者均具有较好的效果,但是PTED手术较FD手术创伤更小、能更及时有效的降低血清疼痛相关因子。

To explore the difference in clinical effects of percutaneous transforaminal endoscopic discectomy(PTED)and fenestration discectomy(FD)in the treatment of lumbar disc herniation(LDH)patients.94 patients with LDH were divided into 47 cases of PTED group and FD group according to the surgical method.The results showed,compared to the FD group,the length of surgical incision,the amount of surgical bleeding,and the length of hospital stay,and the levels of serum IL-1β,IL-6,TNF-αand PGE2 in the PTED group were significantly lower.The ODI index of the PTED group was not significantly different between the two groups at 3 months and 6 months after surgery.Results indicate that both PTED and FD have good results in the treatment of LDH patients,but PTED surgery is less traumatic than FD surgery,and can reduce serum pain-related factors more timely and effectively.