川崎病合并面神经麻痹3例临床分析及文献复习

Clinical analysis and literature review of Kawasaki disease combined with facial nerve palsy 3 cases

目的分析川崎病合并面神经麻痹患儿临床表现、特征、发病机制和治疗,为临床医生提供参考。方法回顾性分析了郑州大学附属河南省儿童医院2020年11月—2021年4月收治的3例川崎病合并面神经麻痹患儿的临床诊治资料,结合相关文献复习,分析川崎病合并面神经麻痹患儿临床表现、特征、发病机制、治疗及预后。结果患儿面神经麻痹经积极治疗恢复正常,但均出现不同程度冠脉损害,其中有1例为巨大冠脉瘤。结论面神经麻痹为川崎病罕见并发症,主要发生于川崎病恢复期,以左侧发病多见,多在3月内恢复正常,绝大多数面神经恢复良好,但川崎病合并面神经麻痹冠脉瘤发生率极高,因此需引起临床医师高度重视。

Objective To analyze the clinical manifestations,characteristics,pathogenesis and treatment of children with Kawasaki disease combined with facial nerve palsy,so as to provide reference for clinicians.Methods We retrospectively analyzed the clinical diagnosis and treatment data of three children with Kawasaki disease combined with facial nerve palsy admitted to Henan Children’s Hospital affiliated to Zhengzhou University,and analyzed the clinical manifestations,characteristics,pathogenesis,treatment and prognosis of children with Kawasaki disease combined with facial nerve palsy by reviewing the relevant literature.Results The children with facial nerve palsy recovered to normal after active treatment,but all of them showed different degrees of coronary artery damage,including one case with a giant coronary artery aneurysm.Conclusion Facial nerve palsy is a rare complication of Kawasaki disease,mainly occurs in the recovery period of Kawasaki disease,with left-sided onset,and most of them recovered normally within 3 months,and most of them recovered well,but,the incidence of coronary artery aneurysms is extremely high when combined with facial nerve palsy,and therefore requires the utmost attention of clinicians.