血小板平均体积预测年龄>60岁STEMI患者PCI术后在院期间预后不良的价值

The value of mean platelet volume for poor prognosis in age >60 years STEMI patients in hospital after PCI

目的:评价血小板平均体积(MPV)评估年龄>60岁急性ST段抬高型心肌梗死(STEMI)患者在院期间预后不良的价值。方法:回顾性分析2017年1月~2018年5月于我院就诊的105例年龄>60岁施行PCI的STEMI患者的住院病历。从中收集所有患者在院期间临床基线资料及MPV,根据患者PCI术后在院治疗期间预后情况分为预后良好组(n=79)及预后不良组(n=26)。比较两组患者临床基线资料及MPV的差异性,同时,采用受试者工作特征曲线(ROC)法评价MPV预测STEMI患者预后不良的价值,此外应用二元logistic回归分析MPV与预后不良的关系。结果:与预后良好组相比,预后不良组MPV水平较高,同时MPV可作为预测在院期间预后不良的指标,其曲线下面积(AUC)(95%CI)为0.88(0.81~0.95),其最佳诊断界值为11.53fL,同时MPV>11.53fL是预后不良的独立危险因素,其优势比(OR)(95%)为9.35(3.10~28.20)。结论:MPV是潜在的预测年龄>60岁STEMI患者在院期间预后不良的指标,同时MPV>11.53fl是预后不良的独立危险因素。

Objective To value of mean platelet volume for poor prognosis in hospital of with age>60 years STEMI patients after PCI.Methods The medical records of 105 STEMI patients with age>60 years who underwent PCI in our hospital from January 2017 to May 2018 were retrospectively reviewed and all of them clinical characteristics and mean platelet volume(MPV)on admission were extracted.All of them were divided into good prognosis group(n=79)and poor prognosis group(n=26)according to prognosis during hospitalization after PCI.The differences between clinical characteristics and MPV were compared between two groups.The receiver operating characteristic curve(ROC)was used to evaluate the value of MPV in predicting poor prognosis in patients with STEMI.In addition,logistic regression analysis was used to analyze the relationship between MPV and poor prognosis.Results Compared with good prognosis group,it had a higher level of MPV in poor prognosis group.The area under curve(AUC)of MPV for poor prognosis were 0.88(0.81~0.95),at the same time,MPV>11.53fl was independent risk factors for poor prognosis with odds ratio(OR)(95%)were 9.35(3.10~28.20).Conclusions MPV was a potential predictor for poor prognosis in STEMI patients with age>60 years and MPV>11.53fL was an independent risk factor for poor prognosis.