舒芬联合瑞芬太尼靶控输注对结直肠癌根治术患者的疗效及对其疼痛应激及血流动力学的影响分析

Comparison of Clinical efficacy、pain stress response and hemodynamics of Remifentanil and Sufentanil for Colorectal cancer patients with Laparoscopic Radical Resection

目的:探讨舒芬联合瑞芬太尼靶控输注对结直肠癌根治术患者的疗效及对其疼痛应激及血流动力学的影响分析。方法:选取我科收治的100例行结直肠癌根治术的患者,根据麻醉方式的不同,分为研究组及对照组两组(各50例),其中研究组采用靶控输注瑞芬太尼与舒芬太尼复合麻醉和对照组采用靶控输注瑞芬太尼麻醉,比较2组患者的临床疗效等差异。结果:研究组患者麻醉后镇痛效果显著优于对照组患者;研究组患者的麻醉后并发症率(6.0%)显著低于对照组患者(22.0%);麻醉3h后两组患者的应激反应相关指标均有所升高,但研究组患者的应激反应相关指标低于对照组;麻醉后3h研究组患者的血流动力学受到的影响较对照组小。结论:舒芬联合瑞芬太尼靶控输注可显著减轻结直肠癌根治术患者的疼痛应激反应,同时降低麻醉后并发症发生率且对术后患者的血流动力学影响小,值得临床大力推广。

Objective To investigate the comparison of clinical efficacy,pain stress response and hemodynamics of remifentanil and sufentanil for colorectal cancer patients with laparoscopic radical Resection.Methods To screening 100 cases of colorectal cancer patients with laparoscopic radical Resection as research subjects,it will be divided into study group with 50 cases and control group with 50 cases,patients in control group were given target controlled infusion of remifentanil and patients in study group were given target controlled infusion of sufentanil and remifentanil,then the two groups were compared in terms of clinical efficacy and so on.Results The analgesic effect indexes in study group were better than the control group;The complications rate in study group was lower than the control group;The pain stress response indexes in study group were better than the control group;The hemodynamics indexes in study group were better than the control group.Conclusion The target controlled infusion of sufentanil and remifentanil in the treatment of colorectal cancer patients with laparoscopic radical resection is significant,it is worthy of popularization and application.