摘要
表面等离子体共振(SPR)生物传感器具有制造成本低、灵敏度高、特异性好、无标记、实时动态检测和准确性高等优点,因此可用于癌症标志物的早期诊断,以监测肿瘤的状况和防止致癌肿瘤的恶化。介绍了SPR生物传感器的检测原理,综述了SPR生物传感器增敏纳米材料及该传感器在癌症标志物检测方面的应用进展,并展望了未来SPR生物传感器的研究方向。
Surface plasmon resonance(SPR)biosensors have the advantages of low manufacturing cost,high.sensitivity,good specificity,label-free,real-time dynamic detection,and high accuracy.Therefore,it has been used for early diagnosis of cancer markers to monitor the condition of tumors and prevent the deterioration of carcinogenic tumors.This article introduced the detection principle of SPR biosensors,summarized the sensitization nanomaterials used to construct SPR biosensors and the application progress of SPR sensors in cancer markers detection,and looked forward to the future research directions of SPR biosensors.
作者
陈凯歌
何诣函
杨美若
王明花
Chen Kaige;He Yihan;Yang Meiruo;Wang Minghua(College of Material and Chemical Engineering,Zhengzhou University of Light Industry,Zhengzhou 450001)
出处
《化工新型材料》
CAS
CSCD
北大核心
2023年第S02期135-140,149,共7页
New Chemical Materials
基金
河南省重点科技攻关项目(222102310153)
郑州轻工业大学大学生研究训练计划项目(2022183)
