瑞舒伐他汀联合中医针药疗法治疗痰浊阻遏型高胆固醇血症患者的效果分析

Analysis of the Effect of Rosuvastatin Combined with Traditional Chinese Medicine Acupuncture and Medicine Therapy on Patients with Phlegm Turbidity Obstruction Type Hypercholesterolemia

目的评估瑞舒伐他汀联合中医针药疗法治疗痰浊阻遏型高胆固醇血症患者的疗效及安全性。方法选择本院2022年9月—2023年10月收治的60例痰浊阻遏型高胆固醇血症患者为研究对象。采用随机数字表法将其分为对照组和试验组,各30例。对照组采用瑞舒伐他汀治疗,试验组采用瑞舒伐他汀联合中医针药疗法。对比两组的治疗总有效率、血脂水平、中医证候积分、体质量、腰围及不良反应发生率。结果试验组治疗总有效率为100.00%,高于对照组的86.67%,差异有统计学意义(P<0.05)。治疗后,试验组总胆固醇水平为(4.55±0.86)mmol/L,三酰甘油水平为(1.14±0.57)mmol/L,低密度脂蛋白胆固醇水平为(2.53±0.74)mmol/L,均低于对照组的(5.87±0.98)mmol/L、(2.05±0.66)mmol/L、(3.62±0.75)mmol/L,而高密度脂蛋白胆固醇水平为(1.65±0.43)mmol/L,高于对照组的(1.21±0.32)mmol/L,组间差异有统计学意义(P<0.05)。治疗后,试验组中医证候积分、体质量均低于对照组,腰围小于对照组,组间差异有统计学意义(P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论瑞舒伐他汀联合中医针药疗法对痰浊阻遏型高胆固醇血症患者具有显著疗效,且安全性较高,该联合疗法值得在临床中进一步推广和应用。

Objective To evaluate the efficacy and safety of rosuvastatin combined with traditional Chinese medicine acupuncture and medicine therapy in patients with phlegm turbidity obstruction type hypercholesterolemia.Methods Sixty patients with phlegm obstruction type hypercholesterolemia admitted to our hospital from September 2022 to October 2023 were selected as the research subjects.The research subjects were divided into a control group and an experimental group using a random number table method,with 30 cases in each group.The control group was treated with rosuvastatin,while the experimental group was treated with rosuvastatin combined with traditional Chinese medicine acupuncture and medicine therapy.Compare the total effective rate,blood lipid levels,traditional Chinese medicine syndrome scores,body mass,waist circumference,and incidence of adverse reactions between two groups of treatments.Results The total effective rate of the experimental group was 100.00%,which was higher than the control group's 86.67%,and the difference was statistically significant(P<0.05).After treatment,the levels of total cholesterol was(4.55±0.86)mmol/L,triglycerides level was(1.14±0.57)mmol/L,and low-density lipoprotein cholesterol level was(2.53±0.74)mmol/L in the experimental group were all lower than(5.87±0.98)mmol/L,(2.05±0.66)mmol/L,and(3.62±0.75)mmol/L in the control group,while the level of high-density lipoprotein cholesterol(1.65±0.43)mmol/L were higher than(1.21±0.32)mmol/L in the control group,the differences between groups were statistically significant(P<0.05).After treatment,the traditional Chinese medicine syndrome score and body mass of the experimental group were lower than those of the control group,the waist circumference of the experimental group were lower than that of the control group,and the differences between groups were statistically significant(P<0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion The combination of rosuvastatin and traditional Chinese medicine acupuncture medicine therapy has significant therapeutic effects and high safety for patients with phlegm turbidity obstruction type hypercholesterolemia.This combination therapy is worthy of further promotion and application in clinical practice.