染色体核型分析在产前诊断中的应用及对出生缺陷的预防价值分析

Application of karyotype analysis in prenatal diagnosis and its value in the prevention of birth defects

目的探讨染色体核型分析在产前诊断中的应用及对出生缺陷的预防价值。方法研究对象为2018.6-2020.6月在我院分娩的180例产妇,根据不同的产前诊断方式将其分为对照组(90例)与观察组(90例),对照组采取常规超声诊断,观察组采取染色体核型分析,将实际情况作为金标准,比较两组产前诊断情况,对出生缺陷者的临床特征进行分析。结果60例存在出生缺陷,观察组的诊断准确率高于对照组(P<0.05)。结论染色体核型分析在产前诊断中具有较高的应用价值,对异常染色体核型情况进行分析,能够有效减少出生缺陷发生风险,具有较高的预防价值,值得临床采纳。

Objective To explore the application of chromosome karyotype analysis in prenatal diagnosis and the prevention value of birth defects.Methods The research object was 180 cases of parturient women who delivered in our hospital from June 2018 to June 2020.According to different prenatal diagnosis methods,they were divided into control group(90 cases)and observation group(90 cases).The control group was diagnosed by conventional ultrasound,and the observation group was analyzed by chromosome karyotype.The clinical characteristics of birth defects were analyzed.Results 60 cases had birth defects,and the diagnostic accuracy of observation group was higher than control group(P<0.05).Conclusion Chromosome karyotype analysis has a high application value in prenatal diagnosis,abnormal chromosome karyotype analysis can effectively reduce the risk of birth defects,has a high prevention value,worthy of clinical adoption.