血清甲状腺球蛋白抗体、抗甲状腺过氧化物酶抗体检测对桥本氏病的临床诊断价值

Clinical diagnostic value of serum thyroglobulin antibody and anti thyroid peroxidase antibody in Hashimoto’s disease

目的探究血清甲状腺球蛋白抗体、抗甲状腺过氧化物酶抗体检测对桥本氏病的临床诊断价值。方法以桥本氏病20例患者为对象,视为研究组,研究时间是2019年3月至2020年9月,体检健康者20例,视为参照组,均检测血清甲状腺球蛋白抗体、抗甲状腺过氧化物酶抗体,对比诊断结果。结果研究组患者的血清甲状腺球蛋白抗体、抗甲状腺过氧化物酶抗体水平均高于参照组,差异有统计学意义(P<0.05)。研究组患者血清甲状腺球蛋白抗体、抗甲状腺过氧化物酶抗体阳性率均高于参照组,差异有统计学意义(P<0.05)。结论桥本氏病患者可使用血清甲状腺球蛋白抗体、抗甲状腺过氧化物酶抗体诊断,有效检出疾病,促进疾病治疗。

Objective To explore the clinical value of serum thyroglobulin antibody and antithyroid peroxidase antibody in the diagnosis of Pons’s disease.Methods Twenty patients with Hashimoto’s disease were selected as the study group from March 2019 to September 2020.Twenty healthy people were selected as the reference group.Serum thyroglobulin antibody and antithyroid peroxidase antibody were detected and the diagnosis results were compared.Results The serum levels of thyroglobulin antibody(263.79±46.83)and antithyroid peroxidase antibody(118.63±26.75)in the study group were both higher than those in the control group,P<0.05,indicating statistically significant difference.The positive rates of serum thyroglobulin antibody and antithyroid peroxidase antibody were higher in the study group than in the control group(P<0.05).Conclusion Serum thyroglobulin antibody and antithyroid peroxidase antibody can be used to diagnose hashimoto’s disease,which can effectively detect the disease and promote its treatment.