基于RAFT调控的聚合诱导自组装研究进展

Research and Development of RAFT-Mediated Polymerization Induced Self-Assembly

可逆加成-断裂链转移(Reversible addition-fragmentation chain transfer,RAFT)聚合被认为是最有效和最具工业化应用前景的可控自由基聚合方法之一。目前基于RAFT调控的聚合诱导自组装(Polymerization induced self-assembly,PISA)技术已成功制备出各种形貌(球形、蠕虫状、棒状、囊泡等)、尺寸(纳米、亚微米)和功能负载的嵌段共聚物纳米颗粒,本文总结了采用不同引发方式介导的RAFT调控PISA技术的应用研究进展,并展望了PISA的未来发展。

Reversible addition-fragmentation chain transfer(RAFT)polymerization is considered as one of the most effective and promising methods for controllable radical polymerization.Recently,polymerization induced self-assembly has been used to prepare block copolymer nanoparticles of various morphologies(spheres,worms,rods,vesicles,etc.),sizes(nano,submicaron)and functional loadings via RAFT polymerization methods.The research and development of RAFT-mediated PISA under different initiation condition were reviewed,and the broad prospects were prospected.