NLRP6 is correlated with the progression and therapeutic outcome of hepatocellular carcinoma and inhibits the function of CD14^+ cells

Objective:Inflammasomes promote carcinogenesis through an extrinsic pathway and maintain the malignant cancer microenvironment through an intrinsic pathway.Moreover,inflammasomes exert anticancer effects by pyroptosis and immune regulatory functions.Until now,there have been few studies about how inflammasomes contribute to hepatocellular carcinoma(HCC)development.