缩宫素+卡前列素氨丁三醇注射液治疗产后出血患者的效果评价

To evaluate the effect of carboprost and tromethamine injection in the treatment of postpartum hemorrhage

目的:分析缩宫素+卡前列素氨丁三醇注射液治疗产后出血患者的效果。方法:选定本院产后出血患者60例,按照随机数字表法分为试验组和对照组,每组各30例,对照组予以缩宫素治疗,试验组患者予以缩宫素+卡前列素氨丁三醇治疗,比较两组产后出血量、出血时间、治疗前后凝血因子指标以及治疗后不良反应发生情况。结果:试验组产后2h以及24h出血量均低于对照组,出血时间短于对照组,P<0.05;治疗前,两组凝血因子指标APTT、PT、FIB比较差异无统计学意义(P>0.05);治疗后,试验组APTT、PT均低于对照组,试验组FIB高于对照组,且两组组内比较治疗后APTT、PT均比治疗前低,FIB均比治疗前高(P<0.05);试验组不良反应发生率(10.00%)与对照组(6.67%)比较差异无统计学意义(P>0.05)。结论:缩宫素+卡前列素氨丁三醇治疗可有效减少产后出血患者产后出血量,缩短出血时间,改善凝血功能,且不良反应较少。

Objective:To analyze the effect of oxytocin+carprost tromethamine injection in the treatment of patients with postpartum hemorrhage.Methods:A total of 60patients with postpartum hemorrhage who were hospitalized in our hospital from January 2019to January 2021were selected and divided into the experimental group and the control group with 30cases in each group according to the“random number table method”.The control group was given oxytocin For treatment,patients in the experimental group were treated with oxytocin+carprost tromethamine,and the amount of postpartum bleeding,bleeding time,coagulation factor indicators before and after treatment,and the occurrence of adverse reactions after treatment were compared between the two groups.Results:The blood loss at 2hand 24hafter delivery in the experimental group was lower than that in the control group,and the bleeding time was shorter than that in the control group,P<0.05;before treatment,there was no statistically significant difference between the two groups of coagulation factor indexes APTT,PT,FIB(P>0.05)After treatment,the APTT and PT of the test group were lower than those of the control group,and the FIB of the test group was higher than that of the control group.In the two groups,APTT and PT after treatment were lower than before treatment,and FIB was higher than before treatment,showing differences All of them have statistical value(P<0.05);the incidence of adverse reactions in the experimental group(10.00%)and the control group(6.67%)have no statistical significance(P>0.05).Conclusion:Oxytocin+carprost tromethamine treatment can effectively reduce the amount of postpartum hemorrhage in patients with postpartum hemorrhage,shorten the bleeding time,improve the coagulation function,and have fewer adverse reactions.