延龄草皂苷类成分及其药理活性、资源保育的研究进展

Research progress on saponins from Trillium tschonoskii and their pharmacological activities and resource conservation

延龄草是土家族四大名药之一,具有活血祛瘀、镇静安神、治疗跌打损伤等功效,现代药理研究表明其在改善阿尔茨海默症等中枢神经退化性疾病方面具有一定疗效。由于早年的大量采挖及现代保育工作尚未完善,延龄草资源稀缺,已被列为国家三级珍稀濒危保护植物。本文归纳了延龄草皂苷类成分及其结构分类、药理活性以及资源保育方面的研究进展,剖析了目前延龄草资源发展中亟待解决的问题,旨在为延龄草资源的可持续利用和产业发展提供基础和依据。

Trillium tschonoskii is one of the four famous medicines of Tujia nationality,which has the effects of promoting blood circulation and removing blood stasis,calming nerves and treating traumatic injuries.Modern pharmacological studies show that it has certain curative effect in improving central nervous degenerative diseases such as Alzheimer’s disease.Due to the massive excavation in the early years and the imperfect modern conservation work,the resource of T.tschonoskii is scarce and has been listed as the national third level rare and endangered plant.In this paper,the research progresses of saponins and their structural classification,pharmacological activity and resource conservation in T.tschonoskii are summarized,and the problems to be solved in the development of T.tschonoskii resources are analyzed,in order to provide the basis and basis for the sustainable utilization and industrial development of T.tschonoskii resources.