摘要
目的:分析本院肾内科艰难梭菌疑似医院感染暴发的原因及预防措施。方法:回顾性分析2018年11月13日至29日本院肾内科发生的3例艰难梭菌感染患者的临床资料。结果:3例患者均为高龄女性(年龄76~82岁),均伴有基础性疾病、腹泻和C反应蛋白升高。3例患者粪便样本均检出产毒型艰难梭菌,tcdB基因阳性。采取规范的消毒隔离、提高手卫生依从性等系列措施,2018年12月至2019年2月肾内科未见艰难梭菌感染病例。结论:艰难梭菌感染暴发可能与患者本身原因及临床科室认识不足有关,针对出现疑似症状的高危患者可根据其临床特征,快速检测,早发现,早诊断,早干预,以减少院内感染播散。
Objective:To determine the causes and preventive measures of suspected nosocomial outbreak of Clostridium difficileinfection(CDI)in the Department of Nephrology of our hospital.Methods:The clinical data of three patients with CDI admitted to the Department of Nephrology in our hospital between November 13 and29,2018 were retrospectively analyzed.Results:All the three patients were elderly females(aged 76-82 years old)with underlying diseases,diarrhea,and elevated C-reactive protein(CRP).The toxigenicClostridium difficile(CD)and positive toxin B gene(tcdB)were detected in stool samples of all three patients.Through a series of measures were used,such as standardized disinfection/isolation and improvement of hand hygiene compliance,no case of CDI was found in the Department of Nephrology between December 2018 and February2019.Conclusion:The outbreak of CDI may be related to the patients’own causes and clinicians’insufficient understanding of CD.For high-risk patients with suspected symptoms,the rapid detection,early detection,early diagnosis,and early intervention may reduce the spread of nosocomial infection based on their clinical characteristics.
作者
修宁宁
潘俊均
邓沛汶
庄云菁
隋洪
Xiu Ningning;Pan Junjun;Deng Peiwen;Zhuang Yunjing;Sui Hong(Dongguan Kanghua Hospital,Dongguan,Guangdong 523080,China)
出处
《广州医科大学学报》
2019年第6期108-110,共3页
Academic Journal of Guangzhou Medical University
基金
东莞市社会科技发展一般项目(2018507150591253).
关键词
艰难梭菌
医院感染暴发
肾内科
Clostridium difficile
nosocomial infection outbreak
nephrology