拟南芥花模式建成多阶段遗传机制

The Multi-stage Genetic Mechanisms of Floral Pattern Formation in Arabidopsis thaliana

花是被子植物的繁殖器官,探究花模式建成对植物进化、形态发育和作物育种等领域的研究均具有十分重要的科学意义。本文所用数据来源于拟南芥(Arabidopsis thaliana)信息资源数据库,包括79个样本的261个基因芯片数据;采用支持向量机算法构建了拟南芥花发育三阶段的蛋白质相互作用网络;利用功能富集分析、网络拓扑结构分析和聚类分析,挖掘出一批与拟南芥花形态发育和花器官形成相关的潜在重要功能基因;基于完善花发育经典的ABCD理论模式,初步阐释了拟南芥花发育的多阶段网络遗传机制。

Flower is the reproductive organ of angiosperms. Floral pattern formation is of great scientific significance for the study of plant evolution, morphological development and crop breeding. The data containing 261 microarray data of 79 samples were obtained from The Arabidopsis thaliana Information Resource Center(TAIR) database, and the three-stage core protein-protein interaction networks of flower development in Arabidopsis thaliana were constructed using support vector machine technology. A batch of potential important functional genes related to the flower morphological development and floral organ formation of A. thaliana were developed through functional enrichment analysis, network topology analysis and cluster analysis. By improving the classic ABCD model of flower development, the genetic mechanisms of multi-stage networks of flower development in A. thaliana were initially explained.