清肝伐脂膏治疗代谢相关脂肪性肝病临床观察

Qinggan Fazhi Ointment in the Treatment of Metabolism-related Fatty Liver Disease

目的观察清肝伐脂膏治疗代谢相关脂肪性肝病的临床疗效。方法选取2023年1月—2023年7月于江西中医药大学附属医院就诊的代谢相关脂肪性肝病患者60例,按随机数字表法分为对照组和观察组,各30例。2组患者均予基础治疗,对照组服用水飞蓟宾,观察组服用清肝伐脂膏,比较2组患者肝功能、血脂、中医证候积分、临床疗效。结果观察组肝功能指标低于对照组(P<0.05);观察组血脂指标改善优于对照组(P<0.05);观察组中医证候积分较对照组更低(P<0.05);观察组临床疗效高于对照组(P<0.05)。结论清肝伐脂膏可明显改善代谢相关脂肪性肝病患者肝功能、血脂及临床症状,提高临床疗效水平。

Objective To observe the clinical efficacy of Qinggan Fazhi ointment in the treatment of metabolism-related fatty liver disease.Methods A total of 60 patients with metabolism-related fatty liver disease who visited Affiliated Hospital of Jiangxi University of Chinese Medicine from January 2023 to July 2023 were selected and divided into control group and observation group according to random number table method,with 30 cases in each group.The control group was treated with silybin,and the observation group was treated with Qinggan Fazhi ointment.Liver function,blood lipid,TCM symptom score and overall clinical effect were compared between the two groups.Results The liver function index of observation group was lower than that of control group(P<0.05).The improvement of blood lipid index in observation group was better than that in control group(P<0.05).The TCM syndrome score of the observation group was lower than that of the control group(P<0.05).The clinical effect of observation group was higher than that of control group(P<0.05).Conclusion Qinggan Fazhi ointment can significantly improve liver function,blood lipids and clinical symptoms in patients with metabolism-related fatty liver disease,and improve clinical efficacy.