436名献血员肝功能状态及乙肝病毒感染标志的血清流行病学调查

Seroepidemiological Survey of Liver Function Status and Markers of Hepatitis B Virus in 436 Blood Donors

本研究用放免法和改良赖氏法,对哈尔滨市436名献血员进行乙肝病毒感染标志和肝功能状态的复检。结果HB_sAg阳性率为2.06%、抗-HB_s阳性率为37.16%、抗-HB_c阳性率为45.18%,HBV总感染率为55.96%,肝功能异常率为8.49%。并观察到献血员的年龄、献血年限和献血员的来源等与HBV感染间有一定关系。

The markers of hepatitis B virus and liver function of 436 blood donors in Harbin City were reexamined by radio-immunoassay and modified Reitman method respectively. The results indicated that the positivity rates of HBsAg, anti-HBs,anti-HBc were 2.06%, 37.16% and 45.18% respectively. The overall HBV infection rate was 55.96% and rate of abnormal liver function was 8.49%. Certain relationship could be found between the age of the donors, years of their blood donation, source of donors and HBV infection.