直肠癌术后放疗期间并发感染的危险因素及臭氧治疗仪预防效果观察

The Risk Factors of Infection Complicated Amidst Radiotherapy after Rectal Cancer Surgery,and the Efficacy of Preventing it By Using Ozone Therapeutic Device

目的:探讨直肠癌术后放疗期间并发感染的危险因素及臭氧治疗仪预防效果。方法:将88例行直肠癌术后放疗患者随机分为观察组和对照组,每组44例。对照组患者在放疗期间采用常规护理,观察组在对照组的基础上采用臭氧治疗仪治疗,比较2组患者术后放疗期间感染发生率。根据是否感染分为感染组和非感染组。记录患者相关资料,分析影响发生感染的单因素,采用多因素Logistic回归分析其危险因素。结果:观察组患者感染发生率明显低于对照组(P<0.05)。感染组急诊手术、合并糖尿病、血清蛋白水平<35g/L、切口长度≥15cm、手术时间≥180min、TNM分期≥Ⅲ期、术后造瘘、术区污染所占比均高于未感染组(P<0.05);经Logistic回归分析显示,急诊手术、合并糖尿病、血清蛋白<35g/L、切口长度≥15cm、手术时间≥180min、TNM分期≥Ⅲ期、术区污染是影响直肠癌术后放疗期间并发感染的独立危险因素(P<0.05)。结论:直肠癌术后放疗期间采用臭氧治疗仪预防能一定程度上降低术后感染发生率,分析发现合并糖尿病、急诊手术、血清蛋白水平<35g/L、切口长度≥15cm、手术时间≥180min、TNM分期≥Ⅲ期、术区污染是影响直肠癌术后放疗期间患者并发感染的独立危险因素。

Objective To search for the risk factors of infection complicated amidst radiotherapy after rectal cancer surgery,and preventive efficacy of ozone therapeutic device.Methods Randomly divided 88 patients surgically treated in author’s hospital to be subject to radiotherapy into control group(44 cases,routine nursing)and observation group(44cases,based on ratine nursing,added with ozone therapeutic device for treatment);then,compared both’s postoperative infection incidence amidst radiotherapy.Afterward,according to with or without infection,again divided the patients into infection group and non-infection group,recorded their relevant data,analysed the mono-factor inducing infection,then,by using multi-variates Logistic regression method analysed the risk factors.Results In infections rate observation group was significantly lower than control group(P<0.05);in emergency operation(1),complicated DM(2),serum protein<35g/L(3),incision length≥15cm(4),operating time≥180min(5),TNM≥Ⅲstage(6),postoperative ostomy(7),and the ratio of operative area contaminated,infection group was all higher non-infection group(P<0.05);Logistic regression analysis shown(1)-(7);as well as operative area comtaminated were independent risk factors(P<0.05).Conclusion Adopting ozone therapeutic device amidst radiotherapy after rectal cancer surgery can reduce postoperative infection’s rate at certain content;whilemeat,above(1)-(7),as well as operative area contaminated are the independent risk factors influencing infections complicated amidst radiotherapy after rectal cancer surgery.